942 research outputs found

    Negotiating equity in UK universities.

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    Description of the project The research involved six case studies of higher education institutions across England, Scotland and Wales. The project aims were:to explore staff experiences of equity issues and institutional equity policies. Participants were drawn from different occupational backgrounds and a variety of socio-cultural groups paying attention also to gender, sexual orientation, ‘race’/ethnicity, disability, age and religio to conduct a critical discourse analysis of equity policies in the six institution to gather the views of senior manager-academics and administrators on their institutional equality policies, and how these relate to national policie to identify challenges, inadequacies, examples of good practice, and constraints/incentives in relation to equity policies at institutional and sector level

    A Physical Theory of the Competition that Allows HIV to Escape from the Immune System

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    Competition within the immune system may degrade immune control of viral infections. We formalize the evolution that occurs in both HIV-1 and the immune system quasispecies. Inclusion of competition in the immune system leads to a novel balance between the immune response and HIV-1, in which the eventual outcome is HIV-1 escape rather than control. The analytical model reproduces the three stages of HIV-1 infection. We propose a vaccine regimen that may be able to reduce competition between T cells, potentially eliminating the third stage of HIV-1.Comment: 5 pages, 2 figures, to appear in Phys. Rev. Let

    Analytical Rebridging Monte Carlo: Application to cis/trans Isomerization in Proline-Containing, Cyclic Peptides

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    We present a new method, the analytical rebridging scheme, for Monte Carlo simulation of proline-containing, cyclic peptides. The cis/trans isomerization is accommodated by allowing for two states of the amide bond. We apply our method to five peptides that have been previously characterized by NMR methods. Our simulations achieve effective equilibration and agree well with experimental data in all cases. We discuss the importance of effective equilibration and the role of bond flexibility and solvent effects on the predicted equilibrium properties.Comment: 29 pages, 8 PostScript figures, LaTeX source. to appear in J. Chem. Phys., 199

    Structure and Response in the World Trade Network

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    We examine how the structure of the world trade network has been shaped by globalization and recessions over the last 40 years. We show that by treating the world trade network as an evolving system, theory predicts the trade network is more sensitive to evolutionary shocks and recovers more slowly from them now than it did 40 years ago, due to structural changes in the world trade network induced by globalization. We also show that recession-induced change to the world trade network leads to an \emph{increased} hierarchical structure of the global trade network for a few years after the recession.Comment: 4 pages, 4 figures, to appear in Phys. Rev. Let

    Reaction, Levy Flights, and Quenched Disorder

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    We consider the A + A --> emptyset reaction, where the transport of the particles is given by Levy flights in a quenched random potential. With a common literature model of the disorder, the random potential can only increase the rate of reaction. With a model of the disorder that obeys detailed balance, however, the rate of reaction initially increases and then decreases as a function of the disorder strength. The physical behavior obtained with this second model is in accord with that for reactive turbulent flow, indicating that Levy flight statistics can model aspects of turbulent fluid transport.Comment: 6 pages, 5 pages. Phys. Rev. E. 65 (2002) 011109--1-
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